منابع مشابه
On Jazz
The question of what is meant by "jazz" seems to mock the clear-cut definitive answer. Just as the historical origins of the form arc disappearing into the fog of the recent past, so its range is disappearing within its ambivalent use at the present moment. For the purpose of providing a crude orientation, one could concede that it is that type of dance music--whether it be used in an unmediate...
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kinase better known for triggering DNA replication also helps create the sticky heterochromatin at centromeres of fission yeast, according to Julie Bailis, Susan Forsburg (Salk Institute, La Jolla, CA), and colleagues. The dual action makes sense, as chromosomes must be stuck together as soon as they are replicated. The responsible kinase activity, Hsk1 (CDC7)–Dfp1, is restricted to S phase, wh...
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Antiviral innate immune responses are a critical first line of host defense against invading viral pathogens (Akira et al., 2006; Takeuchi and Akira, 2010; Moresco et al., 2011). Viral RNA and DNA is initially recognized by pattern recognition receptors (PRRs) such as TLRs, retinoic acid– inducible gene-I (RIG-I)–like receptors (RLRs), Nod-like receptors (NLRs), and cyclic GMP-AMP (cGAMP) synth...
متن کاملRIOK3 keeps MDA5 inactive.
RIG-I and MDA5 are cytoplasmic RNA sensors that recognize dsRNA patterns and activate MAVS to induce innate antiviral gene program. RNA sensing is regulated by ubiquitination in RIG-I while by phosphorylation in MDA5. Thus, de novo phosphorylation is an essential step for keeping MDA5 inactive. We identified a protein kinase RIO kinase 3 (RIOK3) targeting MDA5, and here discuss its possible rel...
متن کاملStudio Music and Jazz
The mission of the Studio Music and Jazz Instrumental Degree Programs is to: (1) prepare jazz instrumentalists to enter the music profession or further jazz studies; (2) identify, recruit, and retain high quality students who seek to pursue studio/jazz performance as a career; (3) foster faculty creativity and performance which serves as a role model for students; (4) develop, and revise course...
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ژورنال
عنوان ژورنال: Miranda
سال: 2021
ISSN: 2108-6559
DOI: 10.4000/miranda.40623